SCHEMBL19986121

SCHEMBL19986121

c1ccc(-c2cccc(-c3nc(-c4ccccc4)nc(-n4c5ccccc5c5c6c7ccccc7c7ccccc7c6c6c7ccccc7oc6c54)n3)c2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.35
TSHR P16473 4/20 0.35
ALDH1A1 P00352 4/20 0.33
LMNA P02545 4/20 0.33
KDM4E B2RXH2 3/20 0.33
HSD17B10 Q99714 2/20 0.33
POLB P06746 2/20 0.33
HPGD P15428 1/20 0.33
MAPK1 P28482 1/20 0.33
KMT2A Q03164 3/20 0.33
MEN1 O00255 2/20 0.33
NPSR1 Q6W5P4 1/20 0.33
USP2 O75604 1/20 0.32
HTT P42858 1/20 0.32
PLA2G2A P14555 1/20 0.32
PLA2G4A P47712 1/20 0.32
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19986120 0.93 MAPT (0.38) MAPTTSHRALDH1A1LMNAKDM4E
SCHEMBL19986118 0.93 MAPT (0.39) MAPTTSHRALDH1A1LMNAKDM4E
SCHEMBL22199913 0.93 MAPT (0.36) MAPTTSHRALDH1A1LMNAKDM4E
SCHEMBL22011566 0.89 MAPT (0.34) MAPTTSHRALDH1A1LMNAKDM4E
SCHEMBL19986200 0.88 PLA2G2A (0.32) MAPTKMT2AMEN1PLA2G2APLA2G4A
SCHEMBL19986122 0.88 MAPT (0.36) MAPTTSHRALDH1A1LMNAKDM4E
SCHEMBL22011564 0.88 MAPT (0.33) MAPTTSHRALDH1A1LMNAKDM4E
SCHEMBL17405648 0.88 MAPT (0.40) MAPTTSHRALDH1A1LMNAKDM4E
SCHEMBL22011560 0.88 MAPT (0.32) MAPTTSHRALDH1A1LMNAKDM4E
SCHEMBL22708875 0.87 PRKDC (0.36) MAPTTSHRALDH1A1LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180083202-A1 COMPOUND FOR ORGANIC OPTOELECTRIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-03-22 US disclosed
US-20180083202-A1 COMPOUND FOR ORGANIC OPTOELECTRIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-03-22 US disclosed