SCHEMBL19986171

SCHEMBL19986171

Cc1cc(-c2ccc(-c3ccccc3)cc2)c2ccncc2n1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 6/20 0.51
KDM4E B2RXH2 3/20 0.47
ALDH1A1 P00352 3/20 0.47
MAPT P10636 3/20 0.47
MEN1 O00255 1/20 0.47
LMNA P02545 1/20 0.47
RECQL P46063 1/20 0.47
KMT2A Q03164 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
KDM4C Q9H3R0 1/20 0.44
TNF P01375 1/20 0.44
ATM Q13315 1/20 0.43
PIK3CA P42336 1/20 0.42
ACACA Q13085 1/20 0.41
MAPK10 P53779 1/20 0.41
USP2 O75604 1/20 0.41
HPGD P15428 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
CYP1A2 P05177 1/20 0.41
MAPK1 P28482 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19986173 0.97 ALDH1A1 (0.49) DHODHKDM4EALDH1A1MAPTMEN1
SCHEMBL19986172 0.91 DHODH (0.46) DHODHKDM4EALDH1A1MAPTMEN1
SCHEMBL18731749 0.84 CYP1A2 (0.58) KDM4EALDH1A1MAPTNPSR1ACACA
SCHEMBL1104820 0.80 CYP1A2 (0.62) KDM4EALDH1A1MAPTNPSR1ACACA
Iodide SCHEMBL30847747 0.79 CYP1A2 (0.60) KDM4EALDH1A1MAPTNPSR1ACACA
SCHEMBL28389108 0.78 MAPK1 (0.49) DHODHKDM4EALDH1A1MAPTMEN1
SCHEMBL17532904 0.78 CYP1A2 (0.51) KDM4EALDH1A1MAPTMEN1LMNA
SCHEMBL17932284 0.76 CYP1A2 (0.53) KDM4EALDH1A1MAPTMEN1LMNA
SCHEMBL28317085 0.76 CYP1A2 (0.56) KDM4EALDH1A1MAPTMEN1KMT2A
SCHEMBL19986175 0.74 CYP1A2 (0.55) KDM4EALDH1A1MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180083202-A1 COMPOUND FOR ORGANIC OPTOELECTRIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-03-22 US disclosed