SCHEMBL19986178

SCHEMBL19986178

Cc1nc(-c2cccc(-c3ccccc3)c2)c2ccc3ccccc3c2n1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
MAPT P10636 1/20 0.44
ALDH1A1 P00352 2/20 0.38
CYP1A2 P05177 2/20 0.38
HPGD P15428 1/20 0.38
HSD17B10 Q99714 1/20 0.38
CYP2A6 P11509 2/20 0.38
NTRK1 P04629 1/20 0.37
NTRK3 Q16288 1/20 0.37
FFAR2 O15552 1/20 0.36
PDE7A Q13946 1/20 0.35
PDE7B Q9NP56 1/20 0.35
CYP1A1 P04798 1/20 0.35
CYP1B1 Q16678 1/20 0.35
ADORA2A P29274 2/20 0.35
PDE10A Q9Y233 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
DHODH Q02127 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19169646 0.89 MAOA (0.44) MAOAL3MBTL1MAPTALDH1A1CYP1A2
SCHEMBL19169192 0.89 MAOA (0.46) MAOAL3MBTL1MAPTALDH1A1CYP1A2
SCHEMBL19169484 0.85 MAPT (0.46) MAOAL3MBTL1MAPTALDH1A1CYP1A2
SCHEMBL17279569 0.84 CYP1A1 (0.43) MAOAL3MBTL1MAPTALDH1A1CYP1A2
SCHEMBL17279572 0.84 CYP1A1 (0.43) MAOAL3MBTL1MAPTALDH1A1CYP1A2
SCHEMBL17279526 0.84 CYP1A1 (0.46) MAOAL3MBTL1MAPTALDH1A1CYP1A2
SCHEMBL17279399 0.82 CYP1A1 (0.45) MAOAL3MBTL1MAPTALDH1A1CYP1A2
SCHEMBL17279409 0.82 CYP1A1 (0.48) MAOAL3MBTL1MAPTALDH1A1CYP1A2
SCHEMBL17279525 0.82 CYP1A1 (0.48) MAOAL3MBTL1MAPTALDH1A1CYP1A2
SCHEMBL17279428 0.82 CYP1A1 (0.48) MAOAL3MBTL1MAPTALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180083202-A1 COMPOUND FOR ORGANIC OPTOELECTRIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-03-22 US disclosed