Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.34 |
| ▸ | ACR | P10323 | 1/20 | 0.34 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20251275 | 1.00 | MAPT (0.39) | MAPTHTTTHRBNPC1LMNA | |
| SCHEMBL19986314 | 0.99 | MAPT (0.40) | MAPTHTTTHRBNPC1LMNA | |
| SCHEMBL19986313 | 0.95 | MAPT (0.36) | MAPTHTTTHRBNPC1LMNA | |
| SCHEMBL18118965 | 0.90 | HTT (0.43) | MAPTHTTTHRBNPC1LMNA | |
| SCHEMBL1656795 | 0.90 | HTT (0.43) | MAPTHTTTHRBNPC1LMNA | |
| SCHEMBL14588420 | 0.89 | THRB (0.43) | MAPTHTTTHRBNPC1LMNA | |
| SCHEMBL12604112 | 0.88 | HTT (0.46) | MAPTHTTTHRBNPC1LMNA | |
| SCHEMBL18363010 | 0.87 | HTT (0.43) | MAPTHTTTHRBNPC1LMNA | |
| SCHEMBL18200237 | 0.87 | THRB (0.43) | MAPTHTTTHRBNPC1LMNA | |
| SCHEMBL17716769 | 0.86 | HTT (0.44) | MAPTHTTTHRBNPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180079957-A1 | POLYMERIZABLE LIQUID CRYSTAL COMPOUNDS, POLYMERIZABLE LIQUID CRYSTAL COMPOSITIONS, LIQUID CRYSTALLINE POLYMERS, PHASE DIFFERENCE FILM AND DISPLAY DEVICE | JNC CORPORATION (JP) | 2018-03-22 | — | — | US | disclosed |