Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK17B | O94768 | 1/20 | 0.41 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.39 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ATR | Q13535 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17564554 | 0.77 | NPR3 (0.42) | STK17BSTK17ASERPINE1PCSK9GAA | |
| SCHEMBL17208821 | 0.77 | ATR (0.51) | STK17BSTK17AMAPTTRPA1GAA | |
| SCHEMBL15724548 | 0.73 | STK17B (0.52) | STK17BSTK17APCSK9AAK1TRPA1 | |
| SCHEMBL20991784 | 0.73 | AAK1 (0.45) | STK17BSTK17APCSK9AAK1TRPA1 | |
| SCHEMBL15136109 | 0.72 | PCSK9 (0.41) | STK17BSTK17AMAPTSERPINE1PCSK9 | |
| SCHEMBL12274268 | 0.70 | CA1 (0.51) | SERPINE1GAASYKMEN1KMT2A | |
| SCHEMBL1457816 | 0.70 | MEN1 (0.46) | SERPINE1PCSK9AAK1GAASYK | |
| SCHEMBL556588 | 0.70 | MEN1 (0.46) | SERPINE1PCSK9AAK1GAASYK | |
| SCHEMBL9600202 | 0.70 | MEN1 (0.46) | SERPINE1PCSK9AAK1GAASYK | |
| SCHEMBL535548 | 0.70 | ATR (0.48) | STK17BSTK17AMAPTGAAATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050110-A1 | NOVEL CAPSID PROTEIN ASSEMBLY INHIBITOR | 正大天晴药业集团股份有限公司 | 2018-03-22 | — | — | WO | disclosed |