SCHEMBL19986483

SCHEMBL19986483

CCC1(CN)CC[Si](C)(C)CC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL419710 0.79
SCHEMBL10285378 0.74
SCHEMBL9968719 0.74
SCHEMBL12062489 0.72 USP2 (0.48)
SCHEMBL14533548 0.72 USP2 (0.48)
SCHEMBL860503 0.72 USP2 (0.48)
SCHEMBL14338106 0.69 KDM4E (0.33)
SCHEMBL1463811 0.68
SCHEMBL23766374 0.67
SCHEMBL11643831 0.65 NCF1 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018050110-A1 NOVEL CAPSID PROTEIN ASSEMBLY INHIBITOR 正大天晴药业集团股份有限公司 2018-03-22 WO disclosed