Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | TYR | P14679 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23194332 | 0.85 | LMNA (0.34) | LMNAHPGDGFERHSD17B10TRPA1 | |
| SCHEMBL25684096 | 0.71 | LMNA (0.38) | LMNAHPGDGFERHSD17B10TRPA1 | |
| SCHEMBL5520992 | 0.68 | LMNA (0.39) | LMNAHPGDGFERHSD17B10TRPA1 | |
| SCHEMBL9886765 | 0.68 | LMNA (0.39) | LMNAHPGDGFERHSD17B10TRPA1 | |
| SCHEMBL17721660 | 0.66 | HPGD (0.36) | LMNAHPGDGFERHSD17B10TRPA1 | |
| SCHEMBL564823 | 0.65 | — | — | |
| SCHEMBL70197 | 0.64 | LMNA (0.35) | LMNAHPGDGFERHSD17B10TRPA1 | |
| SCHEMBL4473883 | 0.63 | LMNA (0.52) | LMNAHPGDGFERHSD17B10TRPA1 | |
| SCHEMBL4898197 | 0.63 | LMNA (0.52) | LMNAHPGDGFERHSD17B10TRPA1 | |
| SCHEMBL3430968 | 0.63 | KCNH2 (0.35) | LMNAHPGDGFERHSD17B10TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050110-A1 | NOVEL CAPSID PROTEIN ASSEMBLY INHIBITOR | 正大天晴药业集团股份有限公司 | 2018-03-22 | — | — | WO | disclosed |