Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.31 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | GLA | P06280 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
| ▸ | PNMT | P11086 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19986448 | 0.81 | MAPT (0.40) | MAPTITGB1ITGA4MEN1ALDH1A1 | |
| SCHEMBL19986722 | 0.76 | ITGB1 (0.45) | MAPTITGB1ITGA4MEN1ALDH1A1 | |
| SCHEMBL8923850 | 0.74 | MAPT (0.50) | MAPTITGB1ITGA4MEN1ALDH1A1 | |
| SCHEMBL28588323 | 0.71 | MAPT (0.42) | MAPTITGB1ITGA4KDM4EP2RX7 | |
| SCHEMBL28577662 | 0.69 | HTR2A (0.35) | HTR2AHTR2CMEN1ALDH1A1GLA | |
| SCHEMBL19986724 | 0.68 | ITGB1 (0.42) | MAPTITGB1ITGA4P2RX7 | |
| SCHEMBL22863914 | 0.67 | HRH4 (0.42) | HTR2AHTR2CMEN1ALDH1A1GLA | |
| SCHEMBL19986447 | 0.64 | STK17B (0.41) | MAPTMEN1KMT2AKDM4EGAA | |
| SCHEMBL15688690 | 0.64 | MAPT (0.41) | MAPTITGB1ITGA4P2RX7 | |
| SCHEMBL7970914 | 0.62 | MAPT (0.41) | MAPTMEN1ALDH1A1GLAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050110-A1 | NOVEL CAPSID PROTEIN ASSEMBLY INHIBITOR | 正大天晴药业集团股份有限公司 | 2018-03-22 | — | — | WO | disclosed |