Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | BTN3A1 | O00481 | 6/20 | 0.39 |
| ▸ | P2RY6 | Q15077 | 4/20 | 0.35 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.35 |
| ▸ | NT5E | P21589 | 1/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.34 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.31 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21511174 | 1.00 | CYP3A4 (0.48) | CYP3A4CYP2C9BTN3A1P2RY6P2RY14 | |
| SCHEMBL19987244 | 0.92 | CYP3A4 (0.46) | CYP3A4CYP2C9BTN3A1P2RY6P2RY14 | |
| SCHEMBL19987165 | 0.88 | CYP3A4 (0.52) | CYP3A4CYP2C9BTN3A1NT5E | |
| SCHEMBL19987255 | 0.88 | CYP3A4 (0.52) | CYP3A4CYP2C9BTN3A1NT5E | |
| SCHEMBL21511228 | 0.88 | CYP3A4 (0.52) | CYP3A4CYP2C9BTN3A1NT5E | |
| SCHEMBL19987178 | 0.84 | CYP3A4 (0.52) | CYP3A4CYP2C9BTN3A1 | |
| SCHEMBL19987148 | 0.83 | CYP3A4 (0.48) | CYP3A4CYP2C9BTN3A1P2RY6P2RY14 | |
| SCHEMBL19987334 | 0.83 | CYP3A4 (0.42) | CYP3A4CYP2C9BTN3A1P2RY6P2RY12 | |
| SCHEMBL19987303 | 0.83 | CYP3A4 (0.42) | CYP3A4CYP2C9NT5E | |
| SCHEMBL19987240 | 0.82 | CYP3A4 (0.68) | CYP3A4CYP2C9BTN3A1P2RY6P2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190322693-A1 | NUCLEOSIDE ANALOGUES AND METHODS OF USE THEREOF | LCB PHARMA INC. (CA) | 2019-10-24 | — | — | US | disclosed |
| WO-2018049535-A1 | NUCLEOSIDE ANALOGUES AND METHODS OF USE THEREOF | LCB PHARMA INC. (CA) | 2018-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190322693-A1 | NUCLEOSIDE ANALOGUES AND METHODS OF USE THEREOF | PNP, TYMP, MTAP | CYP3A4 3805/4885CYP2C9 4343/4885BTN3A1 2556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.