Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | P2RY12 | Q9H244 | 8/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.36 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.36 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19987303 | 0.91 | CYP3A4 (0.42) | CYP3A4CYP2C9 | |
| SCHEMBL19987218 | 0.88 | CYP3A4 (0.45) | CYP3A4CYP2C9P2RY12BTN3A1LMNA | |
| SCHEMBL19987160 | 0.84 | DNPH1 (0.46) | CYP3A4CYP2C9 | |
| SCHEMBL21511174 | 0.83 | CYP3A4 (0.48) | CYP3A4CYP2C9P2RY12BTN3A1P2RY2 | |
| SCHEMBL19987147 | 0.83 | CYP3A4 (0.48) | CYP3A4CYP2C9P2RY12BTN3A1P2RY2 | |
| SCHEMBL21511201 | 0.83 | CYP3A4 (0.45) | CYP3A4CYP2C9P2RY12BTN3A1LMNA | |
| SCHEMBL19987308 | 0.83 | CYP3A4 (0.45) | CYP3A4CYP2C9P2RY12BTN3A1LMNA | |
| SCHEMBL19987164 | 0.82 | CYP3A4 (0.44) | CYP3A4CYP2C9P2RY12BTN3A1P2RY2 | |
| SCHEMBL19987203 | 0.82 | NT5E (0.44) | CYP3A4CYP2C9 | |
| SCHEMBL19987288 | 0.82 | CYP3A4 (0.44) | CYP3A4CYP2C9P2RY12BTN3A1P2RY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190322693-A1 | NUCLEOSIDE ANALOGUES AND METHODS OF USE THEREOF | LCB PHARMA INC. (CA) | 2019-10-24 | — | — | US | disclosed |
| WO-2018049535-A1 | NUCLEOSIDE ANALOGUES AND METHODS OF USE THEREOF | LCB PHARMA INC. (CA) | 2018-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190322693-A1 | NUCLEOSIDE ANALOGUES AND METHODS OF USE THEREOF | PNP, TYMP, MTAP | CYP3A4 3805/4885CYP2C9 4343/4885P2RY12 1222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.