Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 11/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.52 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.52 |
| ▸ | PDE2A | O00408 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | PNP | P00491 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.47 |
| ▸ | NT5E | P21589 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19974361 | 1.00 | ADORA2A (0.61) | ADORA2AADORA3ADORA1PDE4DPDE3A | |
| SCHEMBL19987257 | 0.86 | ADORA2A (0.45) | ADORA2AADORA3ADORA1PDE4DPDE3A | |
| SCHEMBL19974375 | 0.86 | ADORA2A (0.45) | ADORA2AADORA3ADORA1PDE4DPDE3A | |
| SCHEMBL21490245 | 0.84 | ADORA2A (0.59) | ADORA2AADORA3ADORA1SMN1; SMN2ADORA2B | |
| SCHEMBL19987253 | 0.84 | ADORA2A (0.59) | ADORA2AADORA3ADORA1SMN1; SMN2ADORA2B | |
| SCHEMBL19961902 | 0.82 | ADORA2A (0.55) | ADORA2AADORA3ADORA1PDE4DPDE3A | |
| SCHEMBL19949236 | 0.79 | ADORA2A (0.79) | ADORA2AADORA3ADORA1PDE4DPDE3A | |
| SCHEMBL30262554 | 0.79 | ADORA2A (0.79) | ADORA2AADORA3ADORA1PDE4DPDE3A | |
| SCHEMBL19987331 | 0.78 | ADORA3 (0.59) | ADORA2AADORA3ADORA1PDE4DPDE3A | |
| SCHEMBL19974382 | 0.78 | ADORA3 (0.59) | ADORA2AADORA3ADORA1PDE4DPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190322693-A1 | NUCLEOSIDE ANALOGUES AND METHODS OF USE THEREOF | LCB PHARMA INC. (CA) | 2019-10-24 | — | — | US | disclosed |
| WO-2018049535-A1 | NUCLEOSIDE ANALOGUES AND METHODS OF USE THEREOF | LCB PHARMA INC. (CA) | 2018-03-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190322693-A1 | NUCLEOSIDE ANALOGUES AND METHODS OF USE THEREOF | PNP, TYMP, MTAP | ADORA2A 146/4885ADORA3 156/4885ADORA1 397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.