SCHEMBL19987328

SCHEMBL19987328

CCCCc1ccc(Nc2ccc(C)c(O)c2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.52
CYP2D6 P10635 3/20 0.52
CYP2C9 P11712 3/20 0.52
CYP1A2 P05177 2/20 0.52
CYP2C19 P33261 2/20 0.52
LMNA P02545 3/20 0.48
MAPT P10636 3/20 0.48
HPGD P15428 2/20 0.48
MAPK1 P28482 2/20 0.48
MEN1 O00255 2/20 0.48
GAA P10253 2/20 0.48
KMT2A Q03164 2/20 0.48
ALOX12 P18054 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
NPC1 O15118 1/20 0.46
HTT P42858 1/20 0.46
RAB9A P51151 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
POLB P06746 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3919619 0.85 HPGD (0.48) ALDH1A1CYP2D6CYP2C9LMNAMAPT
SCHEMBL19993528 0.83 HPGD (0.47) ALDH1A1LMNAMAPTHPGDMAPK1
SCHEMBL1004694 0.81 NPC1 (0.68) ALDH1A1CYP2D6CYP2C9CYP1A2CYP2C19
SCHEMBL14127779 0.81 HPGD (0.58) ALDH1A1LMNAMAPTHPGDMAPK1
SCHEMBL48879 0.81 HPGD (0.58) ALDH1A1LMNAMAPTHPGDMAPK1
SCHEMBL19985673 0.81 TYR (0.56) ALDH1A1LMNAMAPTHPGDMAPK1
SCHEMBL1422741 0.79 HPGD (0.54) ALDH1A1LMNAMAPTHPGDMAPK1
SCHEMBL2542906 0.79 HPGD (0.46) ALDH1A1LMNAMAPTHPGDMAPK1
SCHEMBL9274463 0.78 HPGD (0.50) ALDH1A1LMNAMAPTHPGDMAPK1
SCHEMBL6329259 0.78 CYP3A4 (0.56) ALDH1A1CYP2D6CYP2C9CYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10723969-B2 Lubricant compositions stabilized by mixtures of diarylamine and hydroxydiarylamine antioxidants LANXESS SOLUTIONS US INC. (US) 2020-07-28 US disclosed
US-20180079987-A1 LUBRICANT COMPOSITIONS STABILIZED BY MIXTURES OF DIARYLAMINE AND HYDROXYDIARYLAMINE ANTIOXIDANTS LANXESS SOLUTIONS US INC. 2018-03-22 US disclosed