Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | UNG | P13051 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16542333 | 0.95 | HPGD (0.43) | HPGDMAPTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL3919619 | 0.87 | HPGD (0.48) | HPGDMAPTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL9618028 | 0.84 | GAA (0.60) | HPGDMAPTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL11062435 | 0.83 | HPGD (0.43) | HPGDMAPTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL1031879 | 0.83 | GAA (0.50) | HPGDMAPTMEN1GAAKMT2A | |
| SCHEMBL48879 | 0.82 | HPGD (0.58) | HPGDMAPTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL14127779 | 0.82 | HPGD (0.58) | HPGDMAPTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL1031878 | 0.82 | KMT2A (0.49) | HPGDMAPTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL1422741 | 0.81 | HPGD (0.54) | HPGDMAPTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL9274463 | 0.80 | HPGD (0.50) | HPGDMAPTSMN1; SMN2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1694744-B1 | OLIGOMERS AND POLYMERS | MERCK PATENT GMBH (DE) | 2015-03-04 | — | — | EP | disclosed |
| US-8043722-B2 | Arylene or heteroarylene groups separated by a nitrogen or phosphorus atom; optical device, electroluminescent device, switching device, field effect transistor insulator, integrated circuit | MERCK PATENT GMBH (DE) | 2011-10-25 | — | — | US | disclosed |
| US-8043722-B2 | Arylene or heteroarylene groups separated by a nitrogen or phosphorus atom; optical device, electroluminescent device, switching device, field effect transistor insulator, integrated circuit | MERCK PATENT GMBH (DE) | 2011-10-25 | — | — | US | disclosed |
| US-8043722-B2 | Arylene or heteroarylene groups separated by a nitrogen or phosphorus atom; optical device, electroluminescent device, switching device, field effect transistor insulator, integrated circuit | MERCK PATENT GMBH (DE) | 2011-10-25 | — | — | US | disclosed |
| US-20080217605-A1 | Oligomers and Polymers | MERCK PATENT GMBH (DE) | 2008-09-11 | — | — | US | disclosed |
| US-20080217605-A1 | Oligomers and Polymers | MERCK PATENT GMBH (DE) | 2008-09-11 | — | — | US | disclosed |
| US-20080217605-A1 | Oligomers and Polymers | MERCK PATENT GMBH (DE) | 2008-09-11 | — | — | US | disclosed |
| EP-1694744-A1 | OLIGOMERS AND POLYMERS | MERCK PATENT GmbH (DE) | 2006-08-30 | — | — | EP | disclosed |
| WO-2005056638-A1 | OLIGOMERS AND POLYMERS | MERCK PATENT GMBH (DE) | 2005-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080217605-A1 | Oligomers and Polymers | AR, ARPC3, NMRAL1 | HPGD 4431/4885MAPT 344/4885SMN1; SMN2 815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.