Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 14/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21511223 | 0.89 | NT5E (0.42) | NT5ECYP3A4CYP2C9 | |
| SCHEMBL19987206 | 0.88 | NT5E (0.42) | NT5ECYP3A4CYP2C9 | |
| SCHEMBL19987168 | 0.88 | NT5E (0.52) | NT5E | |
| SCHEMBL19987319 | 0.85 | CYP3A4 (0.42) | NT5ECYP3A4CYP2C9 | |
| SCHEMBL19987222 | 0.84 | CYP3A4 (0.43) | CYP3A4CYP2C9 | |
| SCHEMBL19987270 | 0.84 | NT5E (0.45) | NT5E | |
| SCHEMBL19987335 | 0.84 | NT5E (0.43) | NT5ECYP3A4CYP2C9 | |
| SCHEMBL19987170 | 0.82 | NT5E (0.53) | NT5E | |
| SCHEMBL19987158 | 0.82 | NT5E (0.53) | NT5E | |
| SCHEMBL21511280 | 0.82 | NT5E (0.48) | NT5ECYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018049535-A1 | NUCLEOSIDE ANALOGUES AND METHODS OF USE THEREOF | LCB PHARMA INC. (CA) | 2018-03-22 | — | — | WO | disclosed |