Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.53 |
| ▸ | NT5E | P21589 | 10/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.51 |
| ▸ | CDK1 | P06493 | 2/20 | 0.51 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19974379 | 0.82 | ADORA3 (0.61) | ADORA3ADORA2ANT5EADORA1CDK1 | |
| SCHEMBL19987188 | 0.82 | ADORA3 (0.61) | ADORA3ADORA2ANT5EADORA1CDK1 | |
| SCHEMBL19987204 | 0.79 | NT5E (0.47) | NT5E | |
| SCHEMBL25090698 | 0.79 | ADORA3 (0.60) | ADORA3ADORA2ANT5EADORA1ADORA2B | |
| SCHEMBL19366689 | 0.79 | ADORA3 (0.60) | ADORA3ADORA2ANT5EADORA1ADORA2B | |
| SCHEMBL19366658 | 0.77 | NT5E (0.75) | ADORA3ADORA2ANT5EADORA1ADORA2B | |
| SCHEMBL24600730 | 0.76 | ADORA3 (0.58) | ADORA3ADORA2ANT5EADORA1 | |
| SCHEMBL7080749 | 0.75 | ADORA3 (0.80) | ADORA3ADORA2ANT5EADORA1ADORA2B | |
| SCHEMBL5396253 | 0.75 | ADORA3 (0.80) | ADORA3ADORA2ANT5EADORA1ADORA2B | |
| SCHEMBL7080746 | 0.75 | ADORA3 (0.80) | ADORA3ADORA2ANT5EADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018049535-A1 | NUCLEOSIDE ANALOGUES AND METHODS OF USE THEREOF | LCB PHARMA INC. (CA) | 2018-03-22 | — | — | WO | disclosed |