SCHEMBL19987369

SCHEMBL19987369

COC(=O)C[C@H]1CCCCN1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FDPS P14324 2/20 0.46
SLC6A3 Q01959 5/20 0.42
LMNA P02545 3/20 0.42
SLC6A2 P23975 3/20 0.42
CYP2D6 P10635 2/20 0.42
MEN1 O00255 2/20 0.42
TP53 P04637 2/20 0.42
KMT2A Q03164 2/20 0.42
SLC6A4 P31645 2/20 0.42
ALDH1A1 P00352 2/20 0.42
TSHR P16473 2/20 0.42
CYP1A2 P05177 1/20 0.42
MLNR O43193 1/20 0.42
ABCB11 O95342 1/20 0.42
EGFR P00533 1/20 0.42
FYN P06241 1/20 0.42
CHRM2 P08172 1/20 0.42
CHRM4 P08173 1/20 0.42
HTR1A P08908 1/20 0.42
CHRM5 P08912 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12481120 1.00 FDPS (0.46) FDPSSLC6A3LMNASLC6A2CYP2D6
SCHEMBL645913 1.00 FDPS (0.46) FDPSSLC6A3LMNASLC6A2CYP2D6
Hydrochloric Acid SCHEMBL7301628 0.98 FDPS (0.45) FDPSSLC6A3LMNASLC6A2CYP2D6
Hydrochloric Acid SCHEMBL645912 0.98 FDPS (0.45) FDPSSLC6A3LMNASLC6A2CYP2D6
SCHEMBL642961 0.94 FDPS (0.40) FDPSSLC6A3LMNASLC6A2CYP2D6
SCHEMBL1584792 0.94 FDPS (0.40) FDPSSLC6A3LMNASLC6A2CYP2D6
SCHEMBL3669595 0.94 FDPS (0.40) FDPSSLC6A3LMNASLC6A2CYP2D6
Hydrochloric Acid SCHEMBL617456 0.93 FDPS (0.39) FDPSSLC6A3LMNASLC6A2CYP2D6
Hydrochloric Acid SCHEMBL617457 0.93 FDPS (0.39) FDPSSLC6A3LMNASLC6A2CYP2D6
Hydrochloric Acid SCHEMBL3669594 0.93 FDPS (0.39) FDPSSLC6A3LMNASLC6A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018050546-A1 IMPROVEMENTS IN OR RELATING TO ORGANIC MATERIAL Université de Liège (BE) 2018-03-22 WO disclosed