Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 4/20 | 0.38 |
| ▸ | ESR1 | P03372 | 3/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | HCK | P08631 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.37 |
| ▸ | PRKDC | P78527 | 1/20 | 0.37 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 2/20 | 0.37 |
| ▸ | HSD17B1 | P14061 | 5/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 5/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16627204 | 0.80 | ESR2 (0.42) | ESR2ESR1PIK3CDABL1EGFR | |
| SCHEMBL16911767 | 0.75 | CDC7 (0.39) | ESR2ESR1ARHSD17B1HSD17B2 | |
| SCHEMBL16627980 | 0.75 | HSD17B1 (0.42) | ESR2ESR1PIK3CDABL1EGFR | |
| SCHEMBL16911354 | 0.74 | ESR2 (0.36) | ESR2ESR1PIK3CDABL1EGFR | |
| SCHEMBL16627170 | 0.72 | ESR2 (0.45) | ESR2ESR1PIK3CDABL1EGFR | |
| SCHEMBL18831429 | 0.71 | ESR2 (0.39) | ESR2ESR1ARHSD17B1HSD17B2 | |
| SCHEMBL16273639 | 0.71 | ESR2 (0.40) | ESR2ESR1PIK3CDABL1EGFR | |
| SCHEMBL16273743 | 0.70 | POLB (0.39) | ESR2ESR1PIK3CDABL1EGFR | |
| SCHEMBL16627195 | 0.69 | ESRRA (0.42) | ESR2ESR1ARHSD17B1HSD17B2 | |
| SCHEMBL16910775 | 0.69 | ESR2 (0.45) | ESR2ESR1ARHSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3006440-B1 | TETRAZOLINONE COMPOUND AND APPLICATION OF SAME | SUMITOMO CHEMICAL CO (JP) | 2018-03-21 | — | — | EP | disclosed |