Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 1/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.40 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17616599 | 0.90 | TP53 (0.46) | MAPTSMN1; SMN2CYP2C9CYP2C19TDP1 | |
| SCHEMBL16273716 | 0.89 | TP53 (0.56) | TP53HTTMRGPRX4PTGDR2FOLH1 | |
| SCHEMBL17616602 | 0.83 | TP53 (0.52) | MAPTL3MBTL1MAOBTP53HTT | |
| SCHEMBL17616621 | 0.82 | MRGPRX4 (0.46) | MAPTMAOBTP53HTTMRGPRX4 | |
| SCHEMBL17616657 | 0.82 | MRGPRX4 (0.51) | MAPTSMN1; SMN2CYP2C9CYP2C19TDP1 | |
| SCHEMBL8948906 | 0.81 | RXRA (0.51) | MAPTSMN1; SMN2MAOBTP53HTT | |
| SCHEMBL17616663 | 0.81 | MRGPRX4 (0.54) | MAPTMAOBTP53HTTMRGPRX4 | |
| SCHEMBL17616660 | 0.78 | MRGPRX4 (0.46) | MAPTSMN1; SMN2CYP2C9CYP2C19TDP1 | |
| SCHEMBL16273718 | 0.78 | TP53 (0.64) | TP53HTTMRGPRX4PTGDR2FOLH1 | |
| SCHEMBL16273701 | 0.78 | PTGDR2 (0.39) | MAPTCYP2C9CYP2C19PTGDR2FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3006440-B1 | TETRAZOLINONE COMPOUND AND APPLICATION OF SAME | SUMITOMO CHEMICAL CO (JP) | 2018-03-21 | — | — | EP | disclosed |