Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 5/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18831370 | 0.89 | SMN1; SMN2 (0.39) | SMN1; SMN2NPC1HPGDRAB9ATHRA | |
| SCHEMBL18871635 | 0.81 | SMN1; SMN2 (0.36) | SMN1; SMN2NPC1HPGDRAB9ATHRA | |
| SCHEMBL18831290 | 0.79 | MEN1 (0.37) | HPGDTHRATHRBCD274MAPT | |
| SCHEMBL23506206 | 0.79 | FFAR4 (0.42) | THRATHRBCD274FFAR4FFAR1 | |
| SCHEMBL23506193 | 0.77 | MRGPRX4 (0.38) | SMN1; SMN2NPC1HPGDRAB9ACD274 | |
| SCHEMBL23506112 | 0.77 | FFAR4 (0.37) | CD274FFAR4FFAR1MRGPRX4 | |
| SCHEMBL22059948 | 0.76 | THRA (0.37) | SMN1; SMN2NPC1RAB9ATHRATHRB | |
| SCHEMBL19987539 | 0.75 | CD274 (0.35) | CD274FFAR4FFAR1MRGPRX4 | |
| SCHEMBL20686631 | 0.75 | MRGPRX4 (0.38) | MEN1KMT2AMRGPRX4RXRARXRB | |
| SCHEMBL21317952 | 0.75 | CD274 (0.36) | CD274FFAR4FFAR1MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3006440-B1 | TETRAZOLINONE COMPOUND AND APPLICATION OF SAME | SUMITOMO CHEMICAL CO (JP) | 2018-03-21 | — | — | EP | disclosed |