Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22842969 | 0.84 | CYP11B2 (0.40) | CYP11B2 | |
| SCHEMBL20933092 | 0.77 | TSHR (0.34) | CYP11B2TSHR | |
| SCHEMBL24729093 | 0.69 | CYP11B2 (0.32) | CYP11B2 | |
| SCHEMBL12806968 | 0.69 | — | — | |
| SCHEMBL12304524 | 0.69 | CYP11B2 (0.43) | CYP11B2 | |
| SCHEMBL23399649 | 0.69 | — | — | |
| SCHEMBL25919989 | 0.67 | PI4KA (0.40) | TSHR | |
| SCHEMBL13714026 | 0.67 | — | — | |
| SCHEMBL12293926 | 0.67 | — | — | |
| SCHEMBL18951013 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2961751-B1 | 1,6- DIAZABICYCLO [3,2,1]OCTAN- 7- ONE DERIVATIVES AND THEIR USE IN THE TREATMENT OF BACTERIAL INFECTIONS | WOCKHARDT LTD (IN) | 2018-03-21 | — | — | EP | disclosed |