Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19987911 | 1.00 | JAK2 (0.83) | JAK2NTRK1 | |
| SCHEMBL2694126 | 0.91 | JAK2 (1.00) | JAK2NTRK1 | |
| SCHEMBL4103512 | 0.91 | JAK2 (1.00) | JAK2NTRK1 | |
| SCHEMBL4096265 | 0.91 | JAK2 (1.00) | JAK2NTRK1 | |
| SCHEMBL2694120 | 0.91 | JAK2 (1.00) | JAK2NTRK1 | |
| SCHEMBL23217003 | 0.91 | JAK2 (1.00) | JAK2NTRK1 | |
| SCHEMBL2694582 | 0.91 | JAK2 (1.00) | JAK2NTRK1 | |
| SCHEMBL2696541 | 0.87 | NTRK1 (1.00) | JAK2NTRK1 | |
| SCHEMBL2696544 | 0.87 | NTRK1 (1.00) | JAK2NTRK1 | |
| SCHEMBL29794706 | 0.87 | NTRK1 (1.00) | JAK2NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3299372-A1 | INTERMEDIATE COMPOUNDS FOR THE PREPARATION OFSUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINE COMPOUNDS AS TRK KINASE INHIBITORS | Array Biopharma, Inc. (US) | 2018-03-28 | — | — | EP | disclosed |