SCHEMBL19988082

SCHEMBL19988082

Nc1ccc2c(c1)C(c1ccccc1)(c1ccccc1)c1cc3ccccc3cc1-2

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.50
LMNA P02545 3/20 0.50
KMT2A Q03164 3/20 0.50
KDM4E B2RXH2 2/20 0.50
MAPT P10636 2/20 0.50
MEN1 O00255 2/20 0.50
OPRK1 P41145 1/20 0.50
PDK2 Q15119 3/20 0.45
ALDH1A1 P00352 6/20 0.44
CYP3A4 P08684 3/20 0.44
HSD17B10 Q99714 3/20 0.44
CHEK1 O14757 1/20 0.43
PRKD3 O94806 1/20 0.43
MAP4K4 O95819 1/20 0.43
RET P07949 1/20 0.43
MET P08581 1/20 0.43
PDGFRA P16234 1/20 0.43
FLT1 P17948 1/20 0.43
LTK P29376 1/20 0.43
PRKX P51817 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL940463 0.91 SMN1; SMN2 (0.59) SMN1; SMN2LMNAKMT2AKDM4EMAPT
SCHEMBL29531420 0.86 SMN1; SMN2 (0.69) SMN1; SMN2LMNAKMT2AKDM4EMAPT
SCHEMBL14679630 0.86 SMN1; SMN2 (0.69) SMN1; SMN2LMNAKMT2AKDM4EMAPT
SCHEMBL30208690 0.86 SMN1; SMN2 (0.69) SMN1; SMN2LMNAKMT2AKDM4EMAPT
SCHEMBL29367160 0.84 MEN1 (0.55) SMN1; SMN2LMNAKMT2AKDM4EMAPT
SCHEMBL25615253 0.84 MEN1 (0.55) SMN1; SMN2LMNAKMT2AKDM4EMAPT
SCHEMBL25125684 0.81 PDK2 (0.44) SMN1; SMN2LMNAKMT2AKDM4EMAPT
SCHEMBL18731221 0.81 SMN1; SMN2 (0.49) SMN1; SMN2LMNAKMT2AKDM4EMAPT
SCHEMBL24763450 0.81 KMT2A (0.49) SMN1; SMN2LMNAKMT2AKDM4EMAPT
SCHEMBL30366586 0.81 PDK2 (0.44) SMN1; SMN2LMNAKMT2AKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3296288-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME Samsung Display Co., Ltd. (KR) 2018-03-21 EP disclosed