SCHEMBL940463

SCHEMBL940463

Nc1ccc2c(c1)C(c1ccccc1)(c1ccccc1)c1cc(N)ccc1-2

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.59
KMT2A Q03164 4/20 0.59
LMNA P02545 3/20 0.59
KDM4E B2RXH2 3/20 0.59
MAPT P10636 3/20 0.59
MEN1 O00255 3/20 0.59
OPRK1 P41145 1/20 0.59
CHEK1 O14757 1/20 0.48
PRKD3 O94806 1/20 0.48
MAP4K4 O95819 1/20 0.48
RET P07949 1/20 0.48
MET P08581 1/20 0.48
PDGFRA P16234 1/20 0.48
FLT1 P17948 1/20 0.48
LTK P29376 1/20 0.48
PRKX P51817 1/20 0.48
NEK2 P51955 1/20 0.48
JAK3 P52333 1/20 0.48
BTK Q06187 1/20 0.48
MAP4K2 Q12851 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29531420 0.94 SMN1; SMN2 (0.69) SMN1; SMN2KMT2ALMNAKDM4EMAPT
SCHEMBL14679630 0.94 SMN1; SMN2 (0.69) SMN1; SMN2KMT2ALMNAKDM4EMAPT
SCHEMBL30208690 0.94 SMN1; SMN2 (0.69) SMN1; SMN2KMT2ALMNAKDM4EMAPT
SCHEMBL19988082 0.91 SMN1; SMN2 (0.50) SMN1; SMN2KMT2ALMNAKDM4EMAPT
SCHEMBL24763450 0.89 KMT2A (0.49) SMN1; SMN2KMT2ALMNAKDM4EMAPT
SCHEMBL18731221 0.89 SMN1; SMN2 (0.49) SMN1; SMN2KMT2ALMNAKDM4EMAPT
SCHEMBL6138102 0.87 SMN1; SMN2 (0.63) SMN1; SMN2KMT2ALMNAKDM4EMAPT
SCHEMBL30340813 0.87 SMN1; SMN2 (0.63) SMN1; SMN2KMT2ALMNAKDM4EMAPT
SCHEMBL17528670 0.87 LMNA (0.46) SMN1; SMN2KMT2ALMNAKDM4EMAPT
SCHEMBL2450310 0.86 SMN1; SMN2 (0.81) SMN1; SMN2KMT2ALMNAKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023113475-A1 POLYMER AND ORGANIC LIGHT-EMITTING DEVICE USING SAME 주식회사 엘지화학 2023-06-22 WO disclosed
US-20230172057-A1 HETEROCYCLIC COMPOUND CONTAINING HETEROATOM SUBSTITUTED FLUORENE AND OPTOELECTRONIC DEVICE WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2023-06-01 US disclosed
US-8840559-B2 Organic piezoelectric material, ultrasonic oscillator using the material, method for manufacturing the ultrasonic oscillator, ultrasonic probe, and ultrasonic medical diagnostic imaging device KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2014-09-23 US disclosed
US-20110021916-A1 ORGANIC PIEZOELECTRIC MATERIAL, ULTRASONIC OSCILLATOR USING THE MATERIAL, METHOD FOR MANUFACTURING THE ULTRASONIC OSCILLATOR, ULTRASONIC PROBE, AND ULTRASONIC MEDICAL DIAGNOSTIC IMAGING DEVICE KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2011-01-27 US disclosed
US-20110021918-A1 ORGANIC PIEZOELECTRIC MATERIAL FILM, METHOD FOR PRODUCTION OF ORGANIC PIEZOELECTRIC MATERIAL FILM, METHOD FOR PRODUCTION OF ULTRASONIC OSCILLATOR, AND ULTRASONIC MEDICAL IMAGING INSTRUMENT KONICA MINOLTA MEDICAL & GRAPHIC INC. (JP) 2011-01-27 US disclosed
US-20110021917-A1 ORGANIC PIEZOELECTRIC MATERIAL FILM, METHOD FOR PRODUCTION OF THE SAME, METHOD FOR PRODUCTION OF ULTRASONIC OSCILLATOR USING THE SAME, AND ULTRASONIC MEDICAL IMAGING INSTRUMENT KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2011-01-27 US disclosed
US-20110004102-A1 ORGANIC PIEZOELECTRIC MATERIAL, ULTRASONIC OSCILLATOR USING THE SAME, METHOD FOR PRODUCING THE ULTRASONIC OSCILLATOR, ULTRASONIC PROBE AND ULTRASONIC MEDICAL DIAGNOSTIC IMAGING DEVICE KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2011-01-06 US disclosed
CN-101114085-A Liquid crystal aligning agent, liquid crystal aligning film and liquid crystal display device JSR CORP (JP) 2008-01-30 CN disclosed
CN-101109873-A Liquid crystal aligning agent,liquid crystal aligning film and liquid crystal display device JSR CORP (JP) 2008-01-23 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230172057-A1 HETEROCYCLIC COMPOUND CONTAINING HETEROATOM SUBSTITUTED FLUORENE AND OPTOELECTRONIC DEVICE CHRM1, CHRM2, CHRM4 SMN1; SMN2 3262/4885KMT2A 2651/4885LMNA 2667/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.