Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.32 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | HMGCR | P04035 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27926275 | 0.83 | KDM4E (0.33) | KDM4EGABRR1ALDH1A1MAPTPTGS1 | |
| SCHEMBL27555031 | 0.83 | KDM4E (0.33) | KDM4EGABRR1ALDH1A1MAPTPTGS1 | |
| SCHEMBL22973162 | 0.81 | MEN1 (0.35) | KDM4ESLC7A5 | |
| SCHEMBL27809118 | 0.81 | MEN1 (0.35) | KDM4ESLC7A5 | |
| SCHEMBL29957040 | 0.77 | KDM4E (0.39) | KDM4EGABRR1ALDH1A1MAPTPTGS1 | |
| SCHEMBL28705428 | 0.77 | PTGS1 (0.52) | KDM4EGABRR1ALDH1A1MAPTPTGS1 | |
| SCHEMBL8668420 | 0.76 | CHRM1 (0.36) | ALDH1A1MAPTPTGS1CYP2D6HMGCR | |
| SCHEMBL27867633 | 0.75 | RNPEP (0.39) | KDM4EGABRR1ALDH1A1MAPTPTGS1 | |
| SCHEMBL4200267 | 0.75 | KDM4E (0.38) | KDM4EGABRR1ALDH1A1MAPTPTGS1 | |
| SCHEMBL16036703 | 0.75 | KDM4E (0.38) | KDM4EGABRR1ALDH1A1MAPTPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2740738-B1 | PLATINUM COMPOUNDS FOR TREATING CELL PROLIFERATIVE DISEASE, PREPARATION METHODS AND USES THEREOF | BEIJING FSWELCOME TECH DEVELOPMENT CO LTD (CN) | 2018-03-28 | — | — | EP | claimed |