Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.34 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.31 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.30 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27550006 | 0.81 | GABRR1 (0.39) | KDM4EGABRR1ALDH1A1MAPTPTGS1 | |
| SCHEMBL4553889 | 0.76 | ALDH1A1 (0.39) | ALDH1A1MAPTPTGS1SLC7A5 | |
| SCHEMBL19988095 | 0.75 | KDM4E (0.41) | KDM4EGABRR1ALDH1A1MAPTPTGS1 | |
| SCHEMBL9069205 | 0.74 | CHRM1 (0.36) | ALDH1A1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL29957040 | 0.73 | KDM4E (0.39) | KDM4EGABRR1ALDH1A1MAPTPTGS1 | |
| SCHEMBL28705428 | 0.73 | PTGS1 (0.52) | KDM4EGABRR1ALDH1A1MAPTPTGS1 | |
| SCHEMBL27867633 | 0.71 | RNPEP (0.39) | KDM4EGABRR1ALDH1A1MAPTPTGS1 | |
| SCHEMBL16036703 | 0.71 | KDM4E (0.38) | KDM4EGABRR1ALDH1A1MAPTPTGS1 | |
| SCHEMBL5856701 | 0.71 | CYP2D6 (0.30) | — | |
| SCHEMBL6362919 | 0.68 | ALDH1A1 (0.36) | ALDH1A1MAPTPTGS1SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090156646-A1 | PYRIDYLPHENOL COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156646-A1 | PYRIDYLPHENOL COMPOUND AND USE THEREOF | GNRHR, PGR, MC1R | KDM4E 881/4885GABRR1 1458/4885ALDH1A1 3446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.