⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21155413 | 0.90 | KDM4E (0.32) | — | |
| SCHEMBL19988507 | 0.88 | NPC1 (0.30) | — | |
| SCHEMBL19985980 | 0.87 | KDM4E (0.31) | — | |
| SCHEMBL19988657 | 0.87 | ALDH1A1 (0.38) | — | |
| SCHEMBL19988518 | 0.87 | ALDH1A1 (0.39) | — | |
| SCHEMBL19988515 | 0.87 | — | — | |
| SCHEMBL19988501 | 0.86 | KDM4E (0.30) | — | |
| SCHEMBL19988514 | 0.85 | ALDH1A1 (0.34) | — | |
| SCHEMBL22199911 | 0.85 | PRKDC (0.33) | — | |
| SCHEMBL22708599 | 0.84 | LIMK1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512848-B1 | COMPOUNDS WITH CARBAZOLE STRUCTURES | MERCK PATENT GMBH (DE) | 2020-11-18 | — | — | EP | disclosed |
| US-20190214574-A1 | COMPOUNDS WITH CARBAZOLE STRUCTURES | MERCK PATENT GMBH (DE) | 2019-07-11 | — | — | US | disclosed |
| WO-2018050583-A1 | COMPOUNDS WITH CARBAZOLE STRUCTURES | MERCK PATENT GMBH (DE) | 2018-03-22 | — | — | WO | disclosed |