Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | GABRP | O00591 | 2/20 | 0.37 |
| ▸ | GABRD | O14764 | 2/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.37 |
| ▸ | GABRE | P78334 | 2/20 | 0.37 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.37 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.37 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.37 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19988471 | 0.83 | SMN1; SMN2 (0.39) | SMN1; SMN2RAB9AGABRPGABRDGABRA1 | |
| SCHEMBL19988802 | 0.82 | MAPT (0.48) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL19988799 | 0.81 | KDM4E (0.47) | SMN1; SMN2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL19988800 | 0.73 | KDM4E (0.47) | SMN1; SMN2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL19988466 | 0.72 | KDM4E (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL19988459 | 0.72 | KDM4E (0.44) | SMN1; SMN2GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL21155928 | 0.70 | KIF11 (0.51) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL19988468 | 0.70 | MAP2K1 (0.49) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL19988450 | 0.69 | CSNK2A1 (0.42) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL19988469 | 0.69 | MAP2K1 (0.42) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050583-A1 | COMPOUNDS WITH CARBAZOLE STRUCTURES | MERCK PATENT GMBH (DE) | 2018-03-22 | — | — | WO | disclosed |