SCHEMBL19989306

SCHEMBL19989306

Cc1cc(Cl)cc(NC(=O)O)c1

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
NPSR1 Q6W5P4 2/20 0.48
RAB9A P51151 1/20 0.48
P2RX1 P51575 1/20 0.47
TMPRSS4 Q9NRS4 1/20 0.47
L3MBTL1 Q9Y468 2/20 0.46
KDM4E B2RXH2 2/20 0.46
HPGD P15428 1/20 0.46
GPR35 Q9HC97 1/20 0.44
FABP4 P15090 1/20 0.43
HTT P42858 1/20 0.43
THRB P10828 1/20 0.43
RAPGEF4 Q8WZA2 1/20 0.42
F12 P00748 1/20 0.42
GRM4 Q14833 2/20 0.42
ALDH1A1 P00352 1/20 0.42
FADS1 O60427 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30801100 1.00 MAPT (0.48) MAPTMEN1KMT2ANPSR1RAB9A
SCHEMBL711831 0.87 MEN1 (0.61) MAPTMEN1KMT2ANPSR1RAB9A
SCHEMBL25999798 0.86 MEN1 (0.61) MAPTMEN1KMT2ANPSR1RAB9A
SCHEMBL2381677 0.86 MEN1 (0.59) MAPTMEN1KMT2ANPSR1RAB9A
SCHEMBL93283 0.84 NPSR1 (0.55) MAPTMEN1KMT2ANPSR1L3MBTL1
SCHEMBL8952429 0.78 MEN1 (0.47) MAPTMEN1KMT2ANPSR1RAB9A
SCHEMBL3800771 0.78 GRM4 (0.56) MAPTMEN1KMT2ANPSR1RAB9A
SCHEMBL17546644 0.77 THRA (0.40) MAPTMEN1KMT2ANPSR1RAB9A
SCHEMBL29739439 0.77 POLB (0.56) MAPTMEN1KMT2ANPSR1RAB9A
SCHEMBL8569799 0.77 MAPK1 (0.54) MAPTMEN1KMT2ANPSR1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210370270-A1 SEPARATING AGENT FOR OPTICAL ISOMERS DAICEL CORPORATION (JP) 2021-12-02 US claimed
US-20180085734-A1 SEPARATING AGENT FOR OPTICAL ISOMERS DAICEL CORPORATION (JP) 2018-03-29 US claimed
US-12403447-B2 Separating agent for optical isomers DAICEL CORPORATION (JP) 2025-09-02 US disclosed
US-12403447-B2 Separating agent for optical isomers DAICEL CORPORATION (JP) 2025-09-02 US disclosed
CN-117242060-A Isoindolinone compounds 蒙特罗萨医疗公司 2023-12-15 CN disclosed
CN-114428131-B Detection method for resolving diastereoisomers of glycopyrronium bromide intermediate 山东泰合医药科技有限公司 2023-09-15 CN disclosed
WO-2023054507-A1 METHOD FOR PRODUCING STATIONARY PHASE FOR COLUMN CHROMATOGRAPHY 株式会社ダイセル 2023-04-06 WO disclosed
JP-2022109259-A OPTICAL ISOMER SEPARATION AGENT, AND MANUFACTURING METHOD FOR OPTICAL ISOMER SEPARATION AGENT 株式会社ダイセル 2022-07-27 JP disclosed
CN-112578034-B Quality control method of chiral amine micromolecules and salts thereof 广东众生睿创生物科技有限公司 2022-02-11 CN disclosed
US-20210370270-A1 SEPARATING AGENT FOR OPTICAL ISOMERS DAICEL CORPORATION (JP) 2021-12-02 US disclosed
US-20210370270-A1 SEPARATING AGENT FOR OPTICAL ISOMERS DAICEL CORPORATION (JP) 2021-12-02 US disclosed
CN-112578034-A Quality control method of chiral amine micromolecules and salts thereof 广东众生睿创生物科技有限公司 2021-03-30 CN disclosed
US-20180085734-A1 SEPARATING AGENT FOR OPTICAL ISOMERS DAICEL CORPORATION (JP) 2018-03-29 US disclosed
US-20180085734-A1 SEPARATING AGENT FOR OPTICAL ISOMERS DAICEL CORPORATION (JP) 2018-03-29 US disclosed