SCHEMBL1998940

SCHEMBL1998940

CCCCCSCc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.50
CYP1A2 P05177 1/20 0.48
CYP3A4 P08684 1/20 0.48
CYP2D6 P10635 1/20 0.48
CYP2C9 P11712 1/20 0.48
SIGMAR1 Q99720 1/20 0.44
SMN1; SMN2 Q16637 4/20 0.43
LMNA P02545 3/20 0.43
TP53 P04637 2/20 0.43
MAPT P10636 2/20 0.43
DNM1 Q05193 2/20 0.43
HTT P42858 2/20 0.43
ALOX12 P18054 1/20 0.43
ALDH1A1 P00352 2/20 0.42
HPGD P15428 1/20 0.42
MEN1 O00255 1/20 0.42
MAPK1 P28482 1/20 0.42
KMT2A Q03164 1/20 0.42
EPHX2 P34913 1/20 0.42
PKM P14618 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15270722 0.98 CYP2C19 (0.48) CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL9490031 0.98 CYP2C19 (0.48) CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL29003720 0.98 CYP2C19 (0.48) CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL329082 0.98 CYP2C19 (0.48) CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL15270977 0.98 CYP2C19 (0.48) CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL11407928 0.98 CYP2C19 (0.48) CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL11782479 0.98 CYP2C19 (0.48) CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL14402487 0.98 CYP2C19 (0.48) CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL29003717 0.98 CYP2C19 (0.48) CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL15270678 0.98 CYP2C19 (0.48) CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024031242-A1 METHOD FOR SYNTHESIZING ARYL BENZYL THIOETHER COMPOUND 苏州大学 2024-02-15 WO claimed
CN-115286547-A Method for synthesizing aryl benzyl sulfide compound 苏州大学 2022-11-04 CN claimed
WO-2024031242-A1 METHOD FOR SYNTHESIZING ARYL BENZYL THIOETHER COMPOUND 苏州大学 2024-02-15 WO disclosed
CN-115286547-B Method for synthesizing aryl benzyl thioether compound 苏州大学 2023-11-03 CN disclosed
CN-115286547-B Method for synthesizing aryl benzyl thioether compound 苏州大学 2023-11-03 CN disclosed
EP-4230620-A1 SUBSTITUTED N-AMINO-N-BENZOIC ACID URACILS, THEIR SALTS AND USE OF SAID COMPOUNDS AS HERBICIDAL AGENTS Bayer Aktiengesellschaft (DE) 2023-08-23 EP disclosed
CN-115286547-A Method for synthesizing aryl benzyl sulfide compound 苏州大学 2022-11-04 CN disclosed
CN-115286547-A Method for synthesizing aryl benzyl sulfide compound 苏州大学 2022-11-04 CN disclosed
CN-115286547-A Method for synthesizing aryl benzyl sulfide compound 苏州大学 2022-11-04 CN disclosed
EP-3728237-B1 SUBSTITUTED THIOPHENYLURACILS , THEIR SALTS AND USE OF SAID COMPOUNDS AS HERBICIDAL AGENTS SYNGENTA CROP PROTECTION AG (CH) 2022-02-09 EP disclosed
US-9650456-B2 Process for producing polydienes BRIDGESTONE CORPORATION (JP) 2017-05-16 US disclosed
CN-1296349-C Novel propionic acid derivatives ASAHI KASEI PHARMA CORP (JP) 2007-01-24 CN disclosed
WO-2006094633-A1 1- SULFONYL-PI PERDINE- 3 -CARBOXYL I C ACID AMIDE DERIVATIVES AS INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE FOR THE TREATMENT OF TYPE II DIABETES MELLITUS F. HOFFMAN-LA ROCHE AG (CH) 2006-09-14 WO disclosed
US-20060199816-A1 Aryl sulfonyl piperidines GILLESPIE PAUL 2006-09-07 US disclosed
US-7056708-B2 Method of producing polyhydroxyalkanoate from alkane having residue containing aromatic ring in its molecule CANON KABUSHIKI KAISHA (JP) 2006-06-06 US disclosed
EP-1367078-B1 Method of producing polyhydroxyalkanoate from alkane having residue containing aromatic ring in its molecule CANON KK (JP) 2006-04-19 EP disclosed
CN-1649834-A Novel propionic acid derivatives ASAHI KASEI PHARMA CORP (JP) 2005-08-03 CN disclosed
EP-1367078-A2 Method of producing polyhydroxyalkanoate from alkane having residue containing aromatic ring in its molecule CANON KABUSHIKI KAISHA (JP) 2003-12-03 EP disclosed
US-20030207412-A1 Method of producing polyhydroxyalkanoate from alkane having residue containing aromatic ring in its molecule CANON KABUSHIKI KAISHA (JP) 2003-11-06 US disclosed
US-4027037-A ARTHROPOD METAMORPHOSIS INHIBITORS BAYER AKTIENGESELLSCHAFT (DT) 1977-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060199816-A1 Aryl sulfonyl piperidines GPR119, SLC5A2, GLS2 CYP2C19 94/4885CYP1A2 83/4885CYP3A4 219/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.