Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.41 |
| ▸ | HTR2A | P28223 | 6/20 | 0.41 |
| ▸ | HTR2C | P28335 | 4/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.39 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1991515 | 0.91 | RECQL (0.55) | RECQLSMN1; SMN2ALDH1A1SLC6A4HTR2A | |
| SCHEMBL1998303 | 0.89 | RECQL (0.53) | RECQLSMN1; SMN2ALDH1A1SLC6A4HTR2A | |
| SCHEMBL1996125 | 0.85 | PADI4 (0.47) | SLC6A4HTR2AHTR2CADRA1AHRH1 | |
| SCHEMBL1997265 | 0.84 | RECQL (0.46) | RECQLSMN1; SMN2ALDH1A1SLC6A4HTR2A | |
| SCHEMBL1997456 | 0.84 | RECQL (0.55) | RECQLSMN1; SMN2ALDH1A1SLC6A4HTR2A | |
| SCHEMBL1996759 | 0.83 | RECQL (0.47) | RECQLSMN1; SMN2ALDH1A1SLC6A4HTR2A | |
| SCHEMBL1996755 | 0.83 | RECQL (0.47) | RECQLSMN1; SMN2ALDH1A1SLC6A4HTR2A | |
| SCHEMBL1996758 | 0.83 | RECQL (0.47) | RECQLSMN1; SMN2ALDH1A1SLC6A4HTR2A | |
| SCHEMBL1991081 | 0.83 | RECQL (0.49) | RECQLSMN1; SMN2ALDH1A1SLC6A4HTR2A | |
| SCHEMBL1994342 | 0.82 | RECQL (0.55) | RECQLSMN1; SMN2ALDH1A1SLC6A4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | ABBOTT LABORATORIES (US) | 2011-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152243-A1 | NOVEL THIENOPYRROLE COMPOUNDS | TPMT, TSLP, THPO | RECQL 3604/4885SMN1; SMN2 2548/4885ALDH1A1 297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.