⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL424149 | 0.62 | — | — | |
| SCHEMBL26910501 | 0.62 | — | — | |
| SCHEMBL23386 | 0.60 | — | — | |
| SCHEMBL8310549 | 0.60 | — | — | |
| SCHEMBL29625554 | 0.57 | — | — | |
| SCHEMBL555523 | 0.57 | — | — | |
| SCHEMBL21788155 | 0.57 | — | — | |
| SCHEMBL4899596 | 0.55 | — | — | |
| SCHEMBL648167 | 0.55 | — | — | |
| SCHEMBL6216231 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117285547-A | Macrocyclic compounds as modulators of CFTR, pharmaceutical compositions thereof, their use and methods of preparation | 弗特克斯药品有限公司 | 2023-12-26 | — | — | CN | disclosed |
| CN-112004817-B | Macrocyclic compounds as modulators of CFTR, pharmaceutical compositions thereof, their use and methods of preparation | 弗特克斯药品有限公司 | 2023-06-23 | — | — | CN | disclosed |
| US-10568326-B2 | 5-substituted imidazole derivatives | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-02-25 | — | — | US | disclosed |
| US-20190223437-A1 | ACTIVE COMPOUND COMBINATIONS COMPRISING A 5-SUBSTITUTED IMIDAZOLE DERIVATIVE | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-07-25 | — | — | US | disclosed |
| US-20190082691-A1 | NOVEL 5-SUBSTITUTED IMIDAZOLE DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-03-21 | — | — | US | disclosed |
| US-10231453-B2 | 5-substituted imidazole derivatives | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-03-19 | — | — | US | disclosed |
| US-20180084780-A1 | Novel 5-substituted imidazole derivatives | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-03-29 | — | — | US | disclosed |