Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.33 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Triethylene Glycol SCHEMBL20972932 | 0.79 | MEN1 (0.73) | MEN1KMT2ATSHRMAPK1THRB | |
| Tetraethylene Glycol SCHEMBL19990177 | 0.79 | MEN1 (0.73) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL28699289 | 0.77 | — | — | |
| Di(Hydroxyethyl)Ether SCHEMBL28797624 | 0.76 | TSHR (0.71) | MEN1KMT2ATSHRMAPK1THRB | |
| Acetic Acid SCHEMBL20913721 | 0.76 | MEN1 (0.52) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL15380682 | 0.74 | CA12 (0.33) | TSHRALDH1A1CA12CA1CA2 | |
| SCHEMBL29250406 | 0.73 | MEN1 (0.55) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL29251264 | 0.73 | MEN1 (0.55) | MEN1KMT2ATSHRMAPK1THRB | |
| Di(Hydroxyethyl)Ether SCHEMBL29030859 | 0.73 | TSHR (0.50) | MEN1KMT2ATSHRMAPK1THRB | |
| SCHEMBL5854805 | 0.73 | CA2 (0.36) | TSHRTHRBALDH1A1CYP3A4CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10562863-B2 | Heterobifunctional linker | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2020-02-18 | — | — | US | disclosed |
| US-20180086724-A1 | HETEROBIFUNCTIONAL LINKER | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2018-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180086724-A1 | HETEROBIFUNCTIONAL LINKER | MPI, CYBB, CD2BP2 | MEN1 2533/4885KMT2A 2070/4885TSHR 4081/4885 |
| US-10562863-B2 | Heterobifunctional linker | MPI, CYBB, CD2BP2 | MEN1 2533/4885KMT2A 2070/4885TSHR 4081/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.