Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SELE | P16581 | 15/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SELL | P14151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19992226 | 0.84 | SELE (0.68) | SELEALDH1A1THRBMAPK1SELL | |
| SCHEMBL16659817 | 0.77 | SELE (0.74) | SELEMAPK1SELL | |
| SCHEMBL18027906 | 0.76 | SELE (0.71) | SELESELL | |
| SCHEMBL16661828 | 0.76 | SELE (0.71) | SELESELL | |
| SCHEMBL16659819 | 0.76 | SELE (0.70) | SELESELL | |
| SCHEMBL17151748 | 0.75 | SELE (0.74) | SELEMAPK1SELL | |
| SCHEMBL17148785 | 0.75 | SELE (0.74) | SELEMAPK1SELL | |
| SCHEMBL16659822 | 0.75 | SELE (0.74) | SELEMAPK1SELL | |
| SCHEMBL19939764 | 0.75 | SELE (0.74) | SELEMAPK1SELL | |
| SCHEMBL21206345 | 0.75 | SELE (0.67) | SELEALDH1A1THRBSELL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3296310-A1 | E-SELECTIN ANTAGONIST COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | GlycoMimetics, Inc. (US) | 2018-03-21 | — | — | EP | disclosed |