SCHEMBL19992256

SCHEMBL19992256

CCNC(=O)N(C)C(=O)OC

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
GAA P10253 1/20 0.38
CHRNB2 P17787 1/20 0.35
CHRNB4 P30926 1/20 0.35
CHRNA3 P32297 1/20 0.35
CHRNA4 P43681 1/20 0.35
OPRM1 P35372 1/20 0.34
OPRL1 P41146 1/20 0.34
MMP1 P03956 1/20 0.33
MMP2 P08253 1/20 0.33
MMP3 P08254 1/20 0.33
MMP9 P14780 1/20 0.33
MMP8 P22894 1/20 0.33
KMT2A Q03164 2/20 0.32
RAB9A P51151 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
TSHR P16473 1/20 0.32
MEN1 O00255 1/20 0.31
MCL1 Q07820 1/20 0.31
KDM4A O75164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11614140 0.83 ALDH1A1 (0.45) ALDH1A1GAACHRNB2CHRNB4CHRNA3
SCHEMBL8172816 0.83 ALDH1A1 (0.45) ALDH1A1GAACHRNB2CHRNB4CHRNA3
SCHEMBL7747516 0.78
SCHEMBL14817327 0.76 ALDH1A1 (0.41) ALDH1A1GAACHRNB2CHRNB4CHRNA3
SCHEMBL20375140 0.74 ALDH1A1 (0.39) ALDH1A1GAACHRNB2CHRNB4CHRNA3
SCHEMBL11690421 0.74 ALDH1A1 (0.39) ALDH1A1GAACHRNB2CHRNB4CHRNA3
Hydrochloric Acid SCHEMBL11690424 0.74 ALDH1A1 (0.39) ALDH1A1GAACHRNB2CHRNB4CHRNA3
SCHEMBL24785862 0.74
SCHEMBL3360045 0.74 ALDH1A1 (0.41) ALDH1A1GAACHRNB2CHRNA4KMT2A
SCHEMBL10014036 0.73 NQO1 (0.35) ALDH1A1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10752728-B2 TDI based low-viscosity polyisocyanates with isocyanurate groups COVESTRO DEUTSCHLAND AG (DE) 2020-08-25 US disclosed
US-10730997-B2 TDI based polyisocyanate mixture with a high solids content COVESTRO DEUTSCHLAND AG (DE) 2020-08-04 US disclosed
US-20190270842-A1 TDI BASED LOW-VISCOSITY POLYISOCYANATES WITH ISOCYANURATE GROUPS COVESTRO DEUTSCHLAND AG (DE) 2019-09-05 US disclosed
US-20190270843-A1 TDI BASED POLYISOCYANATE MIXTURE WITH A HIGH SOLIDS CONTENT COVESTRO DEUTSCHLAND AG (DE) 2019-09-05 US disclosed
US-20180079852-A1 POLYISOCYANATE COMPOSITION BASED ON 1,5-PENTAMETHYLENE DIISOCYANATE COVESTRO DEUTSCHLAND (DE) 2018-03-22 US disclosed