SCHEMBL1999275

SCHEMBL1999275

NC(=O)C1(Cl)CCCCC1

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.33
ALDH1A1 P00352 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
LMNA P02545 2/20 0.33
CYP2C19 P33261 2/20 0.33
USP2 O75604 1/20 0.33
CYP1A2 P05177 1/20 0.33
BLM P54132 1/20 0.33
CACNA2D1 P54289 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1766564 0.85
SCHEMBL1477910 0.74 CYP2C19 (0.42) TSHRALDH1A1SMN1; SMN2LMNACYP2C19
SCHEMBL1421 0.74 CYP2C19 (0.42) TSHRALDH1A1SMN1; SMN2LMNACYP2C19
SCHEMBL2002432 0.74 CYP2C19 (0.32) TSHRALDH1A1SMN1; SMN2LMNACYP2C19
SCHEMBL11825332 0.74 CYP2C19 (0.32) TSHRALDH1A1SMN1; SMN2LMNACYP2C19
SCHEMBL7844653 0.74
SCHEMBL7844660 0.74 KDM4E (0.48)
SCHEMBL6914957 0.72 CYP2C19 (0.41) TSHRALDH1A1SMN1; SMN2LMNACYP2C19
SCHEMBL6917016 0.72 CYP2C19 (0.41) TSHRALDH1A1SMN1; SMN2LMNACYP2C19
Hydrochloric Acid SCHEMBL11815475 0.72 CYP2C19 (0.41) TSHRALDH1A1SMN1; SMN2LMNACYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160369237-A1 METHODS TO ACCELERATE THE ISOLATION OF NOVEL CELL STRAINS FROM PLURIPOTENT STEM CELLS AND CELLS OBTAINED THEREBY ADVANCED CELL TECH INC (US) 2016-12-22 US disclosed
EP-1857471-B1 POLYMERIZATION CATALYST COMPOSITION AND PROCESS FOR PRODUCTION OF POLYMER MITSUI CHEMICALS INC (JP) 2013-04-24 EP disclosed
US-7960305-B2 a mixture of a phosphazenium compound such as tetrakis[tris(dimethylamino)phosphoranylideneamino]phosphonium chloride, transition metal halides and an organic halogen compound as an activator, used for addition homo/copolymerization; living polymers MITSUI CHEMICALS, INC. (JP) 2011-06-14 US disclosed
CN-101128491-B Polymerization catalyst composition and method for producing polymer MITSUI CHEMICALS INC 2010-09-08 CN disclosed
US-20100184033-A1 METHODS TO ACCELERATE THE ISOLATION OF NOVEL CELL STRAINS FROM PLURIPOTENT STEM CELLS AND CELLS OBTAINED THEREBY Lineage Cell Therapeutics, Inc. 2010-07-22 US disclosed
US-20080177014-A1 Polymerization Catalyst Composition and Process for Production of Polymer MITSUI CHEMICALS, INC. (JP) 2008-07-24 US disclosed
US-20080070303-A1 Using myocardial and/or muscle progenitor cells as modeling tool in tissue engineering; regenerative medicine and organ replacement ADVANCED CELL TECHNOLOGY 2008-03-20 US disclosed
CN-101128491-A Polymerization catalyst composition and method for producing polymer MITSUI CHEMICALS INC (JP) 2008-02-20 CN disclosed
EP-1857471-A1 POLYMERIZATION CATALYST COMPOSITION AND PROCESS FOR PRODUCTION OF POLYMER Mitsui Chemicals, Inc. (JP) 2007-11-21 EP disclosed
WO-2007062198-A1 METHODS TO ACCELERATE THE ISOLATION OF NOVEL CELL STRAINS FROM PLURIPOTENT STEM CELLS AND CELLS OBTAINED THEREBY ADVANCED CELL TECHNOLOGY, INC. (US) 2007-05-31 WO disclosed
WO-1992017442-A1 PROCESS FOR THE PREPARATION OF ISOCYANATES AND CARBAMATES USING A SILVER SALT PROMOTED HOFMANN REARRANGEMENT OLIN CORPORATION (US) 1992-10-15 WO disclosed
EP-0060120-B1 PROCESS FOR PREPARING 4-HALOAZETIDIN-2-ONES ELI LILLY AND COMPANY (US) 1984-12-19 EP disclosed