Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | NEK2 | P51955 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1766564 | 0.81 | — | — | |
| SCHEMBL10589523 | 0.77 | KDM4E (0.35) | KDM4EKMT2A | |
| SCHEMBL1999275 | 0.74 | TSHR (0.33) | — | |
| SCHEMBL61405 | 0.72 | KDM4E (0.50) | KDM4EKMT2ANEK2PKMDPP9 | |
| SCHEMBL879719 | 0.72 | KDM4E (0.50) | KDM4EKMT2ANEK2PKMDPP9 | |
| SCHEMBL7844653 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL19641148 | 0.70 | KDM4E (0.48) | KDM4EKMT2ANEK2PKMDPP9 | |
| SCHEMBL2397325 | 0.70 | KDM4E (0.54) | KDM4EKMT2ANEK2PKMDPP9 | |
| Hydrochloric Acid SCHEMBL6780114 | 0.70 | KDM4E (0.48) | KDM4EKMT2ANEK2PKMDPP9 | |
| SCHEMBL18016471 | 0.70 | KDM4E (0.48) | KDM4EKMT2ANEK2PKMDPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112266-A1 | SUBSTITUTED 4-AMINO-2-ARYL-PYRIMIDINES, THEIR PRODUCTION AND USE AND PHARMACEUTICAL PREPARATIONS CONTAINING SAME | Aventis Pharma Deutschland GmbH (DE) | 2001-07-04 | — | — | EP | disclosed |
| WO-2000009496-A1 | SUBSTITUTED 4-AMINO-2-ARYL-PYRIMIDINES, THEIR PRODUCTION AND USE AND PHARMACEUTICAL PREPARATIONS CONTAINING SAME | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2000-02-24 | — | — | WO | disclosed |