⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19243862 | 0.85 | — | — | |
| SCHEMBL14885162 | 0.83 | CARM1 (0.30) | — | |
| SCHEMBL1268586 | 0.83 | — | — | |
| SCHEMBL18913927 | 0.77 | — | — | |
| SCHEMBL14209038 | 0.77 | — | — | |
| SCHEMBL4254586 | 0.75 | CARM1 (0.30) | — | |
| SCHEMBL4265250 | 0.75 | CARM1 (0.30) | — | |
| SCHEMBL4254581 | 0.75 | CARM1 (0.30) | — | |
| SCHEMBL24271569 | 0.75 | CARM1 (0.39) | — | |
| SCHEMBL20807997 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230357193-A1 | COMPOUND CAPABLE OF INHIBITING AND DEGRADING ANDROGEN RECEPTORS, AND PHARMACEUTICAL COMPOSITIONS AND PHARMACEUTICAL USES THEREOF | XIZANG HAISCO PHARMACEUTICALS CO., LTD. (CN) | 2023-11-09 | — | — | US | disclosed |
| EP-4006035-A1 | QUINAZOLINE DERIVATIVES AS TYROSINE KINASE INHIBITORS FOR THE TREATMENT OF CANCER | Neupharma, Inc. (US) | 2022-06-01 | — | — | EP | disclosed |
| WO-2020142729-A1 | INHIBITORS OF CGAS ACTIVITY AS THERAPEUTIC AGENTS | BellBrook Labs (US) | 2020-07-09 | — | — | WO | disclosed |
| WO-2018053447-A1 | PIPERAZINE CARBAMATES AND METHODS OF MAKING AND USING SAME | ABIDE THERAPEUTICS, INC. (US) | 2018-03-22 | — | — | WO | disclosed |