Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.47 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.47 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.46 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14297651 | 0.98 | GPR84 (0.52) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL28509039 | 0.85 | GSR (0.47) | GRIK1GRIK2SLC1A2SLC1A1 | |
| SCHEMBL21224368 | 0.85 | GPR84 (0.50) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL10427910 | 0.83 | GPR84 (0.52) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL14297657 | 0.83 | GPR84 (0.48) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL2015722 | 0.82 | GPR84 (0.55) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL871399 | 0.82 | GPR84 (0.55) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL11777790 | 0.82 | GPR84 (0.55) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL138881 | 0.82 | GPR84 (0.55) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL6930290 | 0.82 | GPR84 (0.55) | GPR84FFAR1MAPTLCKPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2927214-B1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | KYOWA HAKKO KIRIN CO LTD (JP) | 2018-03-21 | — | — | EP | disclosed |