SCHEMBL1999315

SCHEMBL1999315

FC(F)(F)C(F)(F)C(F)(F)C(F)(F)/C=C\C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.37
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL375067 1.00 LMNA (0.37) LMNATHRB
SCHEMBL375068 1.00 LMNA (0.37) LMNATHRB
SCHEMBL11769431 0.96 LMNA (0.42) LMNATHRB
SCHEMBL374952 0.96 LMNA (0.35) LMNA
SCHEMBL1904446 0.96 LMNA (0.42) LMNATHRB
SCHEMBL374953 0.96 LMNA (0.35) LMNA
SCHEMBL10791767 0.96 LMNA (0.42) LMNATHRB
SCHEMBL1904448 0.96 LMNA (0.42) LMNATHRB
SCHEMBL31638108 0.96 LMNA (0.42) LMNATHRB
SCHEMBL333197 0.93 LMNA (0.33) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8418530-B1 Compositions and methods for detecting leaks in HVAC/R systems MAINSTREAM ENGINEERING CORPORATION (US) 2013-04-16 US claimed
US-7960331-B2 Replacement solvents having improved properties and methods of using the same GRZYLL LAWRENCE R 2011-06-14 US claimed
US-7429557-B2 Replacement solvents having improved properties and methods of using the same MAINSTREAM ENGINEERING CORPORATION (US) 2008-09-30 US claimed
US-8418530-B1 Compositions and methods for detecting leaks in HVAC/R systems MAINSTREAM ENGINEERING CORPORATION (US) 2013-04-16 US disclosed
US-7998916-B2 Replacement solvents having improved properties and methods of using the same MAINSTREAM ENGINEERING CORPORATION (US) 2011-08-16 US disclosed
US-7960331-B2 Replacement solvents having improved properties and methods of using the same GRZYLL LAWRENCE R 2011-06-14 US disclosed
US-7566409-B1 Replacement solvents having improved properties for refrigeration flushes MAINSTREAM ENGINEERING CORPORATION (US) 2009-07-28 US disclosed
US-20090026418-A1 Replacement Solvents Having Improved Properties and Methods of Using the Same MAINSTREAM ENGINEERING CORP. (US) 2009-01-29 US disclosed
US-20090005282-A1 Replacement Solvents Having Improved Properties and Methods of Using the Same MAINSTREAM ENGINEERING CORP. (US) 2009-01-01 US disclosed
US-7429557-B2 Replacement solvents having improved properties and methods of using the same MAINSTREAM ENGINEERING CORPORATION (US) 2008-09-30 US disclosed
US-20060166851-A1 Replacement solvents having improved properties and methods of using the same MAINSTREAM ENGINEERING CORP. 2006-07-27 US disclosed