Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 7/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.33 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10046706 | 0.79 | CACNA1B (0.55) | MMP8BCHECACNA1BACHEEPHX1 | |
| SCHEMBL21574176 | 0.77 | EPHX1 (0.34) | MMP8CACNA1BEPHX1 | |
| SCHEMBL25596973 | 0.76 | EPHX1 (0.40) | MMP8EPHX1PLA2G10 | |
| SCHEMBL19200596 | 0.74 | EPHX1 (0.41) | ACHEEPHX1 | |
| SCHEMBL12878807 | 0.71 | EPHX1 (0.39) | ACHEEPHX1 | |
| SCHEMBL25678165 | 0.70 | CYP2D6 (0.34) | MMP8EPHX1 | |
| SCHEMBL20322090 | 0.69 | EPHX1 (0.47) | MMP8EPHX1 | |
| SCHEMBL21664578 | 0.68 | EPHX1 (0.32) | EPHX1 | |
| SCHEMBL18973380 | 0.68 | ALDH1A1 (0.40) | MMP8CACNA1B | |
| SCHEMBL10161455 | 0.68 | ALDH1A1 (0.40) | MMP8CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3296295-A1 | COMPOSITIONS AND METHODS FOR TREATING BETA-AMYLOID RELATED DISEASES | American Life Science Pharmaceuticals, Inc. (US) | 2018-03-21 | — | — | EP | disclosed |