Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLQ | O75417 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6824201 | 0.84 | ALDH1A1 (0.42) | GAAPOLBLMNAALDH1A1THRB | |
| SCHEMBL13041524 | 0.82 | POLQ (0.49) | POLQGAAKDM4EFOLH1HSD17B10 | |
| SCHEMBL8354027 | 0.80 | ALDH1A1 (0.39) | POLQMAPTLMNAALDH1A1MEN1 | |
| SCHEMBL28746503 | 0.79 | FOLH1 (0.49) | POLQGAAKDM4EFOLH1HSD17B10 | |
| SCHEMBL8443795 | 0.78 | POLQ (0.49) | POLQGAAKDM4EFOLH1HSD17B10 | |
| SCHEMBL7506948 | 0.77 | POLQ (0.48) | POLQGAAKDM4EFOLH1HSD17B10 | |
| SCHEMBL22311426 | 0.77 | POLQ (0.48) | POLQGAAKDM4EFOLH1HSD17B10 | |
| SCHEMBL8552126 | 0.77 | POLQ (0.48) | POLQGAAKDM4EFOLH1HSD17B10 | |
| SCHEMBL13041495 | 0.76 | POLQ (0.48) | POLQGAAKDM4EFOLH1HSD17B10 | |
| SCHEMBL24232630 | 0.75 | POLQ (0.40) | POLQGAAKDM4EFOLH1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2927214-B1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | KYOWA HAKKO KIRIN CO LTD (JP) | 2018-03-21 | — | — | EP | disclosed |