SCHEMBL19993376

SCHEMBL19993376

Cc1c(-c2cc(I)c(OC(F)(F)F)c(I)c2)ccc(Cc2ccc(-c3cc(I)c(OC(F)(F)F)c(I)c3)c(I)c2I)c1I

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19993369 0.76 SCN9A (0.33) GPR3
SCHEMBL19993430 0.72 GPR3 (0.41) GPR3
SCHEMBL19993469 0.71 TTR (0.33)
SCHEMBL22621276 0.71 CYP11B1 (0.30) GPR3
SCHEMBL19993375 0.70 ESR1 (0.32)
SCHEMBL19993406 0.70 GPR3 (0.39) GPR3
SCHEMBL19993378 0.69 S1PR1 (0.31) GPR3
SCHEMBL19993372 0.68 GPR3 (0.33) GPR3
SCHEMBL19993408 0.67 GPR3 (0.33) GPR3
SCHEMBL19993443 0.67 KDM4E (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018050573-A1 LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DEVICE MERCK PATENT GMBH (DE) 2018-03-22 WO disclosed