Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.42 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22621150 | 1.00 | DAO (0.45) | DAOKIF11GPR84FFAR1FFAR4 | |
| SCHEMBL9424951 | 0.92 | FAAH (0.53) | ALDH1A1TSHRSLC6A4SLC6A3 | |
| SCHEMBL9425365 | 0.92 | FAAH (0.53) | ALDH1A1TSHRSLC6A4SLC6A3 | |
| SCHEMBL5542757 | 0.92 | DAO (0.40) | DAOKIF11GPR84FFAR1FFAR4 | |
| SCHEMBL9061391 | 0.92 | FAAH (0.53) | ALDH1A1TSHRSLC6A4SLC6A3 | |
| SCHEMBL9060907 | 0.92 | FAAH (0.53) | ALDH1A1TSHRSLC6A4SLC6A3 | |
| SCHEMBL9425192 | 0.92 | FAAH (0.53) | ALDH1A1TSHRSLC6A4SLC6A3 | |
| SCHEMBL5546240 | 0.90 | DAO (0.41) | DAOKIF11GPR84FFAR1FFAR4 | |
| SCHEMBL9061129 | 0.90 | FAAH (0.50) | ALDH1A1TSHRSLC6A4SLC6A3 | |
| SCHEMBL9061958 | 0.90 | FAAH (0.50) | ALDH1A1TSHRSLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512920-B1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DEVICE | MERCK PATENT GMBH (DE) | 2020-11-04 | — | — | EP | disclosed |
| WO-2018050573-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DEVICE | MERCK PATENT GMBH (DE) | 2018-03-22 | — | — | WO | disclosed |