Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.39 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19993409 | 0.91 | NSD2 (0.44) | LOXL2CYP2A6CYP19A1TSHRHSD17B10 | |
| SCHEMBL19993381 | 0.90 | SAE1 (0.39) | LOXL2CYP2A6CYP19A1SAE1UBA2 | |
| SCHEMBL16922701 | 0.79 | NSD2 (0.48) | LOXL2CYP2A6CYP19A1SAE1UBA2 | |
| SCHEMBL19993336 | 0.79 | — | — | |
| SCHEMBL16922705 | 0.79 | NSD2 (0.49) | LOXL2CYP2A6SAE1UBA2TSHR | |
| SCHEMBL19993463 | 0.79 | NSD2 (0.48) | LOXL2CYP2A6CYP19A1SAE1UBA2 | |
| SCHEMBL19993386 | 0.79 | LOXL2 (0.41) | LOXL2CYP2A6CYP19A1SAE1UBA2 | |
| SCHEMBL19993271 | 0.77 | PTGS1 (0.38) | LOXL2CYP11B2CYP11B1 | |
| SCHEMBL16848648 | 0.75 | LOXL2 (0.58) | LOXL2CYP2A6CYP19A1SAE1UBA2 | |
| SCHEMBL14155434 | 0.75 | LOXL2 (0.58) | LOXL2CYP2A6CYP19A1SAE1UBA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512920-B1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DEVICE | MERCK PATENT GMBH (DE) | 2020-11-04 | — | — | EP | disclosed |
| WO-2018050573-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DEVICE | MERCK PATENT GMBH (DE) | 2018-03-22 | — | — | WO | disclosed |