Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.52 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20014453 | 0.92 | ADORA2A (0.51) | ADORA2AADORA2BADORA1ADORA3ALDH1A1 | |
| SCHEMBL19994423 | 0.88 | ADORA2B (0.61) | ADORA2AADORA2BADORA1ADORA3POLB | |
| SCHEMBL19995277 | 0.88 | ADORA2B (0.55) | ADORA2AADORA2BADORA1ADORA3ALDH1A1 | |
| SCHEMBL19995202 | 0.87 | ADORA2A (0.51) | ADORA2AADORA2BADORA1ADORA3 | |
| SCHEMBL19994029 | 0.87 | ADORA2B (0.59) | ADORA2AADORA2BADORA1ADORA3POLB | |
| SCHEMBL19994036 | 0.86 | ADORA2A (0.52) | ADORA2AADORA2BADORA1ADORA3POLB | |
| SCHEMBL19993870 | 0.86 | ADORA2B (0.54) | ADORA2AADORA2BADORA1ADORA3 | |
| SCHEMBL19994032 | 0.86 | ADORA2B (0.51) | ADORA2AADORA2BADORA1ADORA3 | |
| SCHEMBL19994320 | 0.85 | ADORA2B (0.53) | ADORA2AADORA2BADORA1ADORA3 | |
| SCHEMBL19993961 | 0.85 | ADORA2B (0.57) | ADORA2AADORA2BADORA1ADORA3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3515919-A1 | N3-CYCLICALLY SUBSTITUTED THIENOURACILES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2019-07-31 | — | — | EP | disclosed |
| WO-2018054846-A1 | N3-CYCLICALLY SUBSTITUTED THIENOURACILES AND USE THEREOF | BAYER AKTIENGESELLSCHAFT (DE) | 2018-03-29 | — | — | WO | disclosed |
| WO-2018054846-A1 | N3-CYCLICALLY SUBSTITUTED THIENOURACILES AND USE THEREOF | BAYER AKTIENGESELLSCHAFT (DE) | 2018-03-29 | — | — | WO | disclosed |