Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR1 | P21462 | 5/20 | 0.57 |
| ▸ | DPP4 | P27487 | 14/20 | 0.44 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19985880 | 1.00 | FPR1 (0.57) | FPR1DPP4FPR2HCRTR1HCRTR2 | |
| SCHEMBL19972224 | 1.00 | FPR1 (0.57) | FPR1DPP4FPR2HCRTR1HCRTR2 | |
| Hydrochloric Acid SCHEMBL19972420 | 0.99 | FPR1 (0.56) | FPR1DPP4FPR2HCRTR1HCRTR2 | |
| Hydrochloric Acid SCHEMBL19972422 | 0.99 | FPR1 (0.56) | FPR1DPP4FPR2HCRTR1HCRTR2 | |
| SCHEMBL23654002 | 0.83 | FPR1 (0.53) | FPR1DPP4FPR2HCRTR1HCRTR2 | |
| SCHEMBL20581636 | 0.81 | FPR1 (0.50) | FPR1FPR2HCRTR1HCRTR2 | |
| SCHEMBL19972299 | 0.81 | FPR1 (0.71) | FPR1FPR2 | |
| SCHEMBL19985879 | 0.80 | FPR1 (0.56) | FPR1DPP4 | |
| Hydrochloric Acid SCHEMBL19972295 | 0.79 | FPR1 (0.55) | FPR1DPP4 | |
| Hydrochloric Acid SCHEMBL19972298 | 0.79 | FPR1 (0.55) | FPR1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3515902-A1 | 6-MEMBERED CYCLIC AMINES OR LACTAMES SUBSTITUTED WITH UREA AND PHENYL | Grünenthal GmbH (DE) | 2019-07-31 | — | — | EP | disclosed |
| WO-2018054549-A1 | 6-MEMBERED CYCLIC AMINES OR LACTAMES SUBSTITUTED WITH UREA AND PHENYL | Grünenthal GmbH (DE) | 2018-03-29 | — | — | WO | disclosed |