Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 18/20 | 0.59 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.59 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.58 |
| ▸ | ACACA | Q13085 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19995286 | 0.92 | ADORA2B (0.59) | ADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL19995044 | 0.92 | ADORA2B (0.70) | ADORA2BADORA2AADORA1ADORA3ACACA | |
| SCHEMBL20015051 | 0.91 | ADORA2B (0.62) | ADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL19994370 | 0.90 | ADORA2B (0.56) | ADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL20014686 | 0.89 | ADORA2B (0.61) | ADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL19994298 | 0.89 | ADORA2B (0.61) | ADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL20014420 | 0.88 | ADORA2B (0.45) | ADORA2BADORA2AADORA1ADORA3ACACA | |
| SCHEMBL20014278 | 0.88 | ADORA2B (0.60) | ADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL20014273 | 0.87 | ADORA2B (0.59) | ADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL20014427 | 0.87 | ADORA2B (0.59) | ADORA2BADORA2AADORA1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3515919-A1 | N3-CYCLICALLY SUBSTITUTED THIENOURACILES AND USE THEREOF | Bayer Aktiengesellschaft (DE) | 2019-07-31 | — | — | EP | disclosed |
| WO-2018054846-A1 | N3-CYCLICALLY SUBSTITUTED THIENOURACILES AND USE THEREOF | BAYER AKTIENGESELLSCHAFT (DE) | 2018-03-29 | — | — | WO | disclosed |
| WO-2018054846-A1 | N3-CYCLICALLY SUBSTITUTED THIENOURACILES AND USE THEREOF | BAYER AKTIENGESELLSCHAFT (DE) | 2018-03-29 | — | — | WO | disclosed |