SCHEMBL199952

SCHEMBL199952

CCCCCCCCCc1cc(C)c(O)c(C)c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 6/20 0.64
CYP3A4 P08684 2/20 0.61
ESR1 P03372 3/20 0.53
ADRA2A P08913 2/20 0.53
ADORA3 P0DMS8 2/20 0.53
TACR2 P21452 2/20 0.53
SLC6A2 P23975 2/20 0.53
SLC6A4 P31645 2/20 0.53
SLC6A3 Q01959 2/20 0.53
PTGS1 P23219 2/20 0.53
ALDH1A1 P00352 2/20 0.53
TP53 P04637 2/20 0.53
HTT P42858 2/20 0.53
KDM4E B2RXH2 1/20 0.53
LMNA P02545 1/20 0.53
SHBG P04278 1/20 0.53
HSPD1 P10809 1/20 0.53
ADRB3 P13945 1/20 0.53
HTR2C P28335 1/20 0.53
HSPE1 P61604 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28884108 1.00 PTGS2 (0.64) PTGS2CYP3A4ESR1ADRA2AADORA3
SCHEMBL1024720 1.00 PTGS2 (0.64) PTGS2CYP3A4ESR1ADRA2AADORA3
SCHEMBL6211237 1.00 PTGS2 (0.64) PTGS2CYP3A4ESR1ADRA2AADORA3
SCHEMBL28362448 1.00 PTGS2 (0.64) PTGS2CYP3A4ESR1ADRA2AADORA3
SCHEMBL28358896 1.00 PTGS2 (0.64) PTGS2CYP3A4ESR1ADRA2AADORA3
SCHEMBL11762753 1.00 PTGS2 (0.64) PTGS2CYP3A4ESR1ADRA2AADORA3
SCHEMBL7953613 1.00 PTGS2 (0.64) PTGS2CYP3A4ESR1ADRA2AADORA3
SCHEMBL199839 1.00 PTGS2 (0.64) PTGS2CYP3A4ESR1ADRA2AADORA3
SCHEMBL21612724 1.00 PTGS2 (0.64) PTGS2CYP3A4ESR1ADRA2AADORA3
SCHEMBL26045195 1.00 PTGS2 (0.64) PTGS2CYP3A4ESR1ADRA2AADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100383173-C Method of preparing transparent silicone-containing copolycarbonates GEN ELECTRIC (US) 2008-04-23 CN claimed
CN-1263784-C Bisphenol type flame-retardant polycarbonate solution method preparation method WUHAN INST OF CHEMICAL TECHNOL (CN) 2006-07-12 CN claimed
CN-1688630-A Method of preparing transparent silicone-containing copolycarbonates GEN ELECTRIC (US) 2005-10-26 CN claimed
EP-1543061-A1 METHOD OF PREPARING TRANSPARENT SILICONE-CONTAINING COPOLYCARBONATES GENERAL ELECTRIC COMPANY (US) 2005-06-22 EP claimed
CN-1569920-A Bisphenol type flame-retardant polycarbonate solution method preparation method WUHAN INST OF CHEMICAL TECHNOL (CN) 2005-01-26 CN claimed
CN-1569919-A Bisphenol type flame-retardant polycarbonate interface method preparation method WUHAN INST OF CHEMICAL TECHNOL (CN) 2005-01-26 CN claimed
US-6833422-B2 Interfacial polymerization of polycarbonates with polysiloxanes, then endcapping to form haze-free polycarbonatepolysiloxane copolymers GENERAL ELECTRIC COMPANY 2004-12-21 US claimed
WO-2004016674-A1 METHOD OF PREPARING TRANSPARENT SILICONE-CONTAINING COPOLYCARBONATES GENERAL ELECTRIC COMPANY (US) 2004-02-26 WO claimed
US-20040039145-A1 Method of preparing transparent silicone-containing copolycarbonates GENERAL ELECTRIC COMPANY 2004-02-26 US claimed
US-6576739-B2 Conversion of the hindered bisphenol to the corresponding bischloroformate and subsequent treatment with an amine catalyst and an aqueous base to effect polymerization by hydrolysis and condenstation of bischloroformate groups GENERAL ELECTRIC COMPANY 2003-06-10 US claimed
US-20020111456-A1 Method of polycarbonate preparation SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2002-08-15 US claimed
WO-2001085825-A2 METHOD OF POLYCARBONATE PREPARATION GENERAL ELECTRIC COMPANY (US) 2001-11-15 WO claimed
WO-2023075489-A1 PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING METABOLIC SYNDROME-RELATED DISEASES, COMPRISING, AS ACTIVE INGREDIENT, DENDROPANAX TRIFIDUS SAP EXTRACT OR COMPOUND DERIVED THEREFROM 국제뇌교육종합대학원대학교 산학협력단 2023-05-04 WO disclosed
CN-110753714-B Aromatic polycarbonate resin, process for producing the same, and aromatic dihydroxy compound 三菱化学株式会社 2022-04-29 CN disclosed
CN-108368247-B Aromatic polycarbonate resin, aromatic polycarbonate resin composition, and method for producing aromatic polycarbonate resin molded article 三菱化学株式会社 2020-08-14 CN disclosed
CN-108368249-B Flow modifier for thermoplastic resin and thermoplastic resin composition containing same 三菱化学株式会社 2020-07-10 CN disclosed
US-20020111456-A1 Method of polycarbonate preparation SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2002-08-15 US disclosed
US-20020035234-A1 Continuous preparation of polycarbonate GENERAL ELECTRIC COMPANY 2002-03-21 US disclosed
WO-2002008311-A2 CONTINUOUS PREPARATION OF POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2002-01-31 WO disclosed
WO-2001085825-A2 METHOD OF POLYCARBONATE PREPARATION GENERAL ELECTRIC COMPANY (US) 2001-11-15 WO disclosed