Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3336241 | 0.87 | ROCK2 (0.65) | ROCK2ROCK1 | |
| SCHEMBL3336238 | 0.87 | ROCK2 (0.65) | ROCK2ROCK1 | |
| SCHEMBL29192409 | 0.85 | ROCK2 (0.67) | ROCK2ROCK1 | |
| SCHEMBL1094664 | 0.83 | ROCK2 (0.51) | ROCK2ROCK1 | |
| SCHEMBL11956270 | 0.83 | ROCK2 (0.58) | ROCK2ROCK1 | |
| SCHEMBL2775044 | 0.82 | ROCK2 (0.56) | ROCK2ROCK1 | |
| SCHEMBL1105002 | 0.81 | ROCK2 (0.72) | ROCK2ROCK1 | |
| SCHEMBL23398166 | 0.81 | ROCK2 (0.47) | ROCK2ROCK1 | |
| SCHEMBL1096576 | 0.80 | ROCK2 (0.55) | ROCK2ROCK1 | |
| Hydrochloric Acid SCHEMBL1095012 | 0.80 | ROCK2 (0.71) | ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2326623-A2 | BETA-AND GAMMA-AMINO-ISOQUINOLINE AMIDE COMPOUNDS AND SUBSTITUTED BENZAMIDE COMPOUNDS | Aerie Pharmaceuticals, Inc. (US) | 2011-06-01 | — | — | EP | disclosed |
| WO-2010011853-A2 | BETA-AND GAMMA-AMINO-ISOQUINOLINE AMIDE COMPOUNDS AND SUBSTITUTED BENZAMIDE COMPOUNDS | AERIE PHARMACEUTICALS, INC. (US) | 2010-01-28 | — | — | WO | disclosed |