Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | BCAT1 | P54687 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 4/20 | 0.38 |
| ▸ | TNKS | O95271 | 1/20 | 0.37 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19997048 | 0.84 | NPC1 (0.51) | TTRNPC1RAB9ABCAT1LMNA | |
| SCHEMBL3557297 | 0.80 | TTR (0.53) | TTRNPC1RAB9ABCAT1LMNA | |
| SCHEMBL23626600 | 0.77 | TTR (0.50) | TTRNPC1RAB9ABCAT1LMNA | |
| SCHEMBL14124715 | 0.76 | TTR (0.59) | TTRNPC1RAB9ABCAT1LMNA | |
| SCHEMBL15071004 | 0.76 | TTR (0.59) | TTRNPC1RAB9ABCAT1LMNA | |
| SCHEMBL3560247 | 0.76 | NPC1 (0.57) | TTRNPC1RAB9ABCAT1LMNA | |
| SCHEMBL22423163 | 0.74 | LMNA (0.41) | TTRNPC1RAB9ABCAT1LMNA | |
| SCHEMBL1222307 | 0.73 | TTR (0.78) | TTRNPC1RAB9ABCAT1LMNA | |
| SCHEMBL18413421 | 0.72 | AKT1 (0.52) | RAB9ALMNAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL10993675 | 0.72 | TTR (0.54) | TTRNPC1RAB9ABCAT1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9929363-B2 | Composition and synthesis of aggregation-induced emission materials | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2018-03-27 | — | — | US | disclosed |